Based on the announcement of the World Health Organization (WHO) in 2018, the Wuhan pneumonia caused by an
unknown etiology should be recognized as the first Disease X. Later, the pathogen was identified to be a novel
coronavirus denoted 2019-nCoV, which has 79.5% and 96% whole genome sequence identify to SARS-CoV and bat
SARS-related coronavirus (SARSr-CoV-RaTG13), respectively, suggesting its potential bat origin. With high human-tohuman transmission rate (R0), 2019-nCoV has quickly spread in China and other countries, resulting in 34,953 confirm
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